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Clinical study of dexmedetomidine combined with ropivacaine for intercostal nerve block combined with general anesthesia in upper abdominal surgery

Clinical study of dexmedetomidine combined with ropivacaine for intercostal nerve block combined with general anesthesia in upper abdominal surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049294
Enrollment
Unknown
Registered
2021-07-29
Start date
2021-01-01
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group 1:General anesthesia induction
Group 2:A total of 40 ml local anesthetic solution was prepared with 20 ml 1% ropivacaine and 20 ml normal saline for intercostal nerve block
Group 3:1% ropivacaine 20 ml, dexmedetomidine 0.8 ug/ kg + 20 ml of normal saline was added to prepare 40 ml local anesthetic solution for intercostal nerve block

Sponsors

The First Affiliated Hospital of Fujian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-75 years; 2. The patient agrees to participate in the research; 3. Complete collection of medical records.

Exclusion criteria

Exclusion criteria: 1. History of allergy to ropivacaine and analogs; 2. There is a history of obvious pain or painful disease before surgery; 3. History of mental illness, alcoholism, and long-term use of analgesics (continuous use of analgesics for more than 3 months); 4. Patients with preoperative liver and kidney insufficiency; 5. Patients with massive intraoperative bleeding; 6. Inability to communicate with patients.

Design outcomes

Primary

MeasureTime frame
VAS pain score; Dosage of anesthetics;Postoperative nausea and vomiting;

Countries

China

Contacts

Public ContactChen Jinzhuan

The First Affiliated Hospital of Fujian Medical University

zhuanzhuan007@126.com+86 13609532681

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026