infertility
Conditions
Interventions
experimental group:GnRH-a+hCG dual trigger
Control group: HCG trigger
Sponsors
Affiliated Hospital of Shandong University of Chinese medicine
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1. Expected NOR (normal ovarian response): AFC 6 to 15; AMH 1.2 ng/ml to 3.5 ng/ml; FSH =50% immature oocytes in a previous IVF cycle triggered with hCG
Exclusion criteria
Exclusion criteria: 1. Age >=40 years 2. BMI >= 30 kg / m2; 3. IVF/ICSI attempts >=3; 4. Those using the natural cycle or mild stimulation for IVF/ICSI treatment; 5. Individuals with severe hyperstimulation ovarian syndrome during controlled ovarian stimulation; 6. Patients with endocrine disorders (diabetes, hyperprolactinemia, hypothyroidism, congenital adrenal hyperplasia, Cushing's syndrome or polycystic ovary syndrome). 7. Untreated moderate and severe endometriosis, submucosal myoma, multiple endometrial polyps, pelvic inflammation, uterine malformation, Asherman syndrome and hydrosalpinx; 8. Abnormal immune function and chromosome karyotype of both spouses; 9. Hypothalamic dysfunction, malignant tumor or other contraindications to in vitro fertilization; 10. Currently participating in another intervention clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| M? oocyte rate;Number of oocytes;Fertilization rate;High quality embryo rate;Blastocyst formation rate;Embryo implantation rate;Biochemical pregnancy rate;Clinical pregnancy rate;Pregnancy loss rate;Live birth rate;The incidence of ovarian hyperstimulation syndrome; | — |
Countries
China
Contacts
Public ContactJingyan Song
Shandong University of traditional Chinese Medicine
Outcome results
None listed