Evaluation of thoracoabdominal nerve block by ultrasound-guided transchondral approach in laparoscopic cholecystectomy

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100049282

Enrollment

Unknown

Registered

2021-07-29

Start date

2021-08-01

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group 1:General anesthesia

Group 2:Perichondral approach for blockage of thoracoabdominal nerves

Group 3:Oblique subcostal transversus abdominis plane block

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 60 years; 2. ASA classification I-II; 3. Elective three-port laparoscopic cholecystectomy is planned.

Exclusion criteria

Exclusion criteria: 1. Those with contraindications to abdominal wall nerve block: abnormal coagulation function, infection at the puncture site, allergy to local anesthetics, etc.; 2. Those with a history of chronic pain or neuropathic pain who have been taking painkillers for a long time; 3. Unable to cooperate with the researcher for any reason: hearing or visual impairment, language comprehension impairment, mental illness, etc.; 4. BMI >=35kg/m^2; 5. Patients with advanced liver and renal insufficiency; 6. Those who have had abdominal surgery in the past; 7. Those who have a history of postoperative nausea and vomiting or suffer from motion sickness; 8. Has participated in other researches.

Design outcomes

Primary

Measure	Time frame
Dosage of sufentanil 24 hours after operation;	—

Secondary

Measure	Time frame
The mean arterial pressure and heart rate of the patients at the time of entering the room, at the time of skin resection, immediately after the establishment of pneumoperitoneum, at the beginning of the cholecystectomy for 5min, at the time of surgical suture and 5min after extubation;Nerve block operation time, extubation time;NRS score at rest and cough;Intraoperative dosage of fentanyl, propofol, and remifentanil;Postoperative analgesic dose of flurbiprofen and dezocine at 12h and 24h;24h postoperative quality of life recovery questionnaire (QoR-40) score;The severity of postoperative nausea and vomiting;Postoperative infection, hematoma, subcutaneous emphysema and shoulder pain;24h postoperative analgesia satisfaction;The number of patients receiving tropisetron in each group after surgery;	—

Measure

Time frame

The mean arterial pressure and heart rate of the patients at the time of entering the room, at the time of skin resection, immediately after the establishment of pneumoperitoneum, at the beginning of the cholecystectomy for 5min, at the time of surgical suture and 5min after extubation;Nerve block operation time, extubation time;NRS score at rest and cough;Intraoperative dosage of fentanyl, propofol, and remifentanil;Postoperative analgesic dose of flurbiprofen and dezocine at 12h and 24h;24h postoperative quality of life recovery questionnaire (QoR-40) score;The severity of postoperative nausea and vomiting;Postoperative infection, hematoma, subcutaneous emphysema and shoulder pain;24h postoperative analgesia satisfaction;The number of patients receiving tropisetron in each group after surgery;

—

Countries

China

Contacts

Public ContactXu Yahui

Affiliated Hospital of Xuzhou Medical University

1371011721@qq.com+86 18755126308

Outcome results