Clinical trial of the efficacy of Q-switched 1064-nm Nd:YAG laser on melasma

A prospective, randomized, self-controlled clinical trial of Q-switched 1064-nm Nd:YAG laser with sub-long pulse width mode loading on melasma after large-spot low-energy mode loading

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100049271

Enrollment

Unknown

Registered

2021-07-28

Start date

2021-08-01

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Melasma

Interventions

Experimental group:Half face adopts LFQS mode, and the other half face adopts LFQS mode and sub-long pulse width mode

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Melasma patients, aged 18-60 years, no gender restriction; 2. Never received the relevant treatment; 3. After fully understanding the treatment plan and risks, patients voluntarily signed an informed consent form, willing to accept self-control trial, and cooperate with follow-up.

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating patients; 2. Allergy to surface anesthetics; 3. Have any active skin disease in the test area; 4. Patients with wound, infection, or epidermal ulceration at the test site; 5. Other factors that the investigator believes may have an impact on the results of the trial.

Design outcomes

Primary

Measure	Time frame
Overall Beauty Improvement Score;Melasma Index;Pigment Index;	—

Countries

China

Contacts

Public ContactZhang Zhen

Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine

zz6503@vip.126.com+86 13817594541

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026