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A non-inferior, randomized controlled clinical trial of a minimally invasive root canal therapy system dominated by erbium laser activation in the treatment of pulpitis

A non-inferior, randomized controlled clinical trial of a minimally invasive root canal therapy system dominated by erbium laser activation in the treatment of pulpitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049264
Enrollment
Unknown
Registered
2021-07-28
Start date
2021-09-01
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulptitis

Interventions

Minimally invasive treatment group:Root canal therapy with minimally mechanical preparation
Conventional treatment group:Root canal therapy with conventional mechanical preparation

Sponsors

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Outpatient diagnosis of pulpitis; 2. The four walls of the affected tooth are intact or single-wall defect; 3. Aged between 18-60 years, no gender limitation; 4. Good oral hygiene; 5. Can sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Serious systemic diseases (such as uncontrolled diabetes, cardiovascular diseases, immune disorders, blood diseases, etc.); 2. Pregnant or lactating patients; 3. Patients with mental illness or a history of mental illness; 4. Patients with infectious diseases (such as hepatitis, syphilis, AIDS patients, etc.); 5. Patients with head and neck tumors, or after radiotherapy of tumor head and neck; 6. Patients who have taken antibiotics in the past three months; 7. Patients with moderate to severe periodontitis; 8. Patients with abnormal salivary gland function; 9. Patients with temporomandibular joint disorder; 10. Patients with night grinding or severely abnormal occlusion; 11. Patients with acid erosion and severe caries; 12. Patients with more than one wall defect after the target tooth has been cleaned of decayed matter or patients who need post-core repair; 13. At present, the patients with the defect located more than 1mm below the gingival after the tooth has been cleaned of decay; 14. At present, the distance between the top and bottom of the pulp chamber is less than 6mm.

Design outcomes

Primary

MeasureTime frame
X-ray of periapical region;

Secondary

MeasureTime frame
Patient visual self-rating;Patient oral scores;

Countries

China

Contacts

Public ContactZhao Jizhi

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences

zhaojizhi@126.com+86 18612671920

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026