None listed
Conditions
Interventions
Experimental group A:Intravenous 2% lidocaine 0.5 mg/kg was given before propofol induction
Experimental group B:Intravenous 2% lidocaine 1 mg/kg was given before propofol induction
Experimental group C:Intravenous 2% lidocaine 1.5 mg/kg was given before propofol induction
Control group D:Intravenous injection of the same amount of normal saline is given before propofol induction
Sponsors
West China Second Hospital of Sichuan University
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Patients with ASA I to II, aged 18-50 years, fasting for 6 hours, and no drinking for 2 hours, who are planning to undergo outpatient abortion and uterine curettage surgery.
Exclusion criteria
Exclusion criteria: 1. Patients with BMI >28 kg/m^2 or BMI<18 kg/m^2 and patients with body weight <40kg. 2. Patients who are allergic to local anesthetics, propofol, fentanil or other drugs related to this study. 3. Patients with severe liver and kidney dysfunction, endocrine disease, metabolic disease, cardiovascular disease, respiratory system disease or central nervous system disease. 4. Patients who have taken sedatives, analgesics, and drugs that may affect the metabolism of local anesthetics for a long time or within 7 days, or patients who have taken other experimental drugs or participated in other clinical trials within 3 months before the study. 5.Patients who are addicted to alcohol or drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whether the patient achieves adequate sedation (MOAA/S score <1) after propofol induction, and whether the patient is physically active during or before dilation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Propofol used in total;Ramsay upper airway obstruction score;Duration of operation;The time from the end of the operation to the opening of the eyes;Hypoxemia (SPO260s); | — |
Countries
China
Contacts
Public ContactNi Juan
West China Second Hospital of Sichuan University
Outcome results
None listed