None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Mechanical ventilation for more than 48 hours; 2. Improvement or recovery of the primary disease leading to mechanical ventilation; 3. Stable oxygenation (oxygenation index>=200mmHg, PEEP<=5cmH2O, inspired oxygen concentration <50%); 4. Hemodynamically stable, no dynamic manifestations of myocardial ischemia, no or only small doses of vasoactive drugs are required to maintain (dopamine <5ug/kg·min or norepinephrine <0.05ug/kg·min); 5. Have the ability to expectorate sputum autonomously.
Exclusion criteria
Exclusion criteria: 1. Abnormal respiratory mechanics caused by previous lung tumor, lung resection, chest wall deformity, etc.; 2. Use muscle relaxants within 48 hours before the study; 3. Those with a history of diaphragmatic paralysis; 4. Patients with neuromuscular disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| diaphragmatic excursion;diaphragmatic thickness;respiratory rate; | — |
Countries
China
Contacts
Affiliated Hospital of Qingdao University