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The efficacy and mechanism study of electroencephalograph bionic therapy on post-stroke cognition dysfunction based on functional Near-Infrared Spectroscopy

The efficacy and mechanism study of electroencephalograph bionic therapy on post-stroke cognition dysfunction based on functional Near-Infrared Spectroscopy: a randomized, single blind trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049190
Enrollment
Unknown
Registered
2021-07-24
Start date
2022-04-01
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Experimental group:electroencephalograph bionic therapy
Control group:electroencephalograph bionic sham therapy

Sponsors

Shanghai First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. Aged 20 to 55 years; 2. Right-handed; 3. The first onset, with unilateral cerebral infarction confirmed by imaging; 4. Cognitive impairment is directly related to cerebrovascular disease, assessed by Mini-mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA), which is consistent with mild post-cerebral infarction cognitive impairment criteria; 5. If there is limb dysfunction, but the Brunnstrom classification of hemiplegia lower limbs is >= grade III, and the muscle tension of the lower limbs (using the modified Ashworth classification) is less than or equal to grade 2; 6. The course of the disease is within 6 weeks, and the blood pressure is controlled within the normal range; 7. The education level is junior high school or above; 8. Voluntarily participate in this study, know and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. History of myocardial infarction, angina pectoris, etc.; 2. Have a history of epilepsy; 3. Those with impaired consciousness; 4. Combined with Parkinson's syndrome, equipped with a pacemaker; severe malnutrition; severe cardiopulmonary disease, respiratory failure; active liver disease, liver and kidney insufficiency; congestive heart failure; malignant progressive hypertension; 5. The course of cerebral infarction exceeds 6 months; 6. Cognitive impairment caused by other diseases; 7. There are visual and hearing impairments; 8. Those who do not cooperate with the treatment.

Design outcomes

Primary

MeasureTime frame
N-back Task;Near infrared test;

Secondary

MeasureTime frame
Variable Frequency Transformer Task;

Countries

China

Contacts

Public ContactDuan Zhouying

Shanghai First People's Hospital

duanzhouying@yeah.net+86 13564174013

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026