Painless Colonoscopy
Conditions
Interventions
Experimental group1:2.5µg/kg alfentanil combined with 2mg/ml propofol
Experimental group2:5.0µg/kg alfentanil combined with 2mg/ml propofol
Experimental group3:7.5µg/kg alfentanil combined with 2mg/ml propofol
Experimental group4:10.0µg/kg alfentanil combined with 2mg/ml propofol
Sponsors
The Second Hospital of Jiaxing
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with ASA I to III; 2. Aged 60 to 80 years; 3. Plan to undergo a painless colonoscopy (expected operation time < 30 minutes); 4. Body mass index 18.5-30 kg/m2.
Exclusion criteria
Exclusion criteria: 1. Patients without written consent; 2. ASAIV level or above; 3. Serious heart disease; 4. Lung disease; 5. Advanced or decompensated liver or kidney disease; 6. Metabolic diseases; 7. Electrolyte disorders; 8. Blood pressure > 180/110mmHg; 9. Allergy to emulsions or opioids; 10. A history of acute airway inflammation, neuromuscular or neuropsychiatric disorders, suspected abuse of narcotic analgesics or sedatives within the previous 2 weeks; 11. Exclude patients with difficult airway management, such as nail-mind spacing <=4cm or Mallampati score of 3 or 4.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygen saturation reduction events [defined as peripheral capillary oxygen saturation below 95% and 90%]; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamic stability;Total consumption of propofol ;Operation time;Postanesthesia care unit retention time;pain score 1 minute after waking up ;Satisfaction of endoscopists, satisfaction of patients ; | — |
Countries
China
Contacts
Public ContactXu Hai
The Second Hospital of Jiaxing
Outcome results
None listed