acute ischemic stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18-80 years; 2. First-episode patients with acute ischemic stroke.(in accordance with the diagnostic criteria of Chinese guidelines for diagnosis and treatment of acute ischemic stroke 2018); 3. Last known well (without neurological symptoms)>4.5hours of treatment initiation. Measurable disabling; neurological deficit (defined as an impairment of one or more of the following: language, motor function, cognition, gaze, vision, neglect); 4. The time from onset to enrolment was less than 24 hours, and stroke onset was defined as the midway point between the sleep onset (or last known normal) and wake time(refer to Int J Stroke. 2012 Jan;7(1):74-80.); 5. Patients who signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Asymptomatic territorial infarction; 2. Patients who declined participation in registration and follow-up investigation; The completed cases included all registration data of patients for 90 days+/-7 days. Patients presenting with one or more of the following conditions would be withdrawn from this study: 1) Patients dissatisfied the inclusion criteria; 2) The patients withdrew the informed consent form; 3) Any situation where the investigators believed that the patients should discontinue from this study for safety reasons or in the interest of the patients4) Patients were lost to follow-up; 5) Others. On termination of the study, patients should be assessed for endpoints. except for patients lost to follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Rankin Scale (mRS);NIHSS; | — |
Secondary
| Measure | Time frame |
|---|---|
| the Barthelindex (BI); | — |
Countries
China
Contacts
Shanghai Pudong Hospital (Fudan University Pudong Medical Center)