dry beriberi
Conditions
Interventions
Case series:Thiamine (intravenous and oral)
Sponsors
Dr. Nayema Masrura
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Any person admitted to CMCH as a Suspected/Possible dry-beriberi. Risk factors + at least 2 of the following signs: Risk factors include Imbalanced diet (diet poor in thiamine/rich in carbohydrate or anti-thiamine factors), malnutrition, alcoholism, GIT surgery, chronic diarrhoea, chronic vomiting, pregnancy or history of recent delivery, chronic. diuretics use, renal dialysis, total parenteral nutrition. 1) Muscle weakness of upper and or lower limb (less than grade 5 power in MRC scale); 2) Positive sensory symptoms (burning, tingling or pain); 3) Objective sensory deficit (pain, touch, position, vibration sense); 4) Absent or reduced deep tendon reflexes; 5) Positive squat test (unable to rise after squatting without help);6) Leg swelling; 2. Aged 18 years and above.
Exclusion criteria
Exclusion criteria: 1. Patients with isolated cardiac/wet beriberi; 2. Patient with known causes of peripheral neuropathy such as Diabetic, hereditary, Demyelinating (GBS, CIDP), metabolic (hepatic/renal impairment), drugs (e.g. INH, Ethambutol, Phenytoin, Metronidazole, Dapsone etc.) Toxin (As ,OPC, Pb ,Hg except alcohol) etc.; 3. Patients refuse to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Improvement; | — |
Countries
Bangladesh
Contacts
Public ContactDr. Nayema Masrura
Assistant Surgeon, Bangladesh Institute of Tropical and Infectious Diseases (BITID), Foujdehat, chittagong, Bangladesh
Outcome results
None listed