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To investigate the efficacy and mechanism of mechanical vibration and routine bladder perfusion in the treatment of neurogenic bladder and urinary tract infection after spinal cord injury based on ultrasound

To investigate the efficacy and mechanism of mechanical vibration and routine bladder perfusion in the treatment of neurogenic bladder and urinary tract infection after spinal cord injury based on ultrasound

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049120
Enrollment
Unknown
Registered
2021-07-21
Start date
2021-08-01
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

urinary tract infection caused by neurogenic bladder after spinal cord injury

Interventions

Experimental group:Mechanical vibration and bladder perfusion
Control group 2:Routine bladder perfusion

Sponsors

Zhongshan Hospital, Xiamen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Subjects with spinal cord injury confirmed by CT or MRI imaging; 2.Eligible subjects must meet the criteria for neurogenic bladder diagnosis; 3.The included qualified subjects met the diagnostic criteria for urinary tract infection: bacteriuria can be diagnosed when the number of bacteria in each ml of clean midstream urine sample is >= 105 or the number of bacteria is in urine, and the possibility of urinary tract infection should be considered; 4.Aged 18 to 80 years; 5.Qualified subjects enrolled should sign informed consent voluntarily, be able to understand and cooperate with relevant examinations, rehabilitation assessment and treatment.

Exclusion criteria

Exclusion criteria: 1.Life is not stable or/and the illness is serious; 2.Subjects whose bladder volume was too small and the bladder pressure was more than 40cmH2O by simple bladder pressure measurement; 3.The patient is being treated with antibiotics; 4.Patients with severe cognitive impairment who are unable to cooperate with examination, evaluation and treatment; 5.Patients were diagnosed with severe heart disease, heart, liver, renal failure, malignant tumor, gastrointestinal bleeding and so on; 6.Patients who are included in other clinical trials that would affect the evaluation results of this study.

Design outcomes

Primary

MeasureTime frame
Quantitative detection of midstream urinary sediment;Midcourse urine culture;Bladder wall thickness, detrusor muscle thickness, detrusor and urethral sphincter functional coordination, residual urine volume;

Secondary

MeasureTime frame
Activities of daily living;Quality of life;

Countries

China

Contacts

Public ContactLin Zhengkun

Zhongshan Hospital, Xiamen University

593327953@qq.com+86 592 5896452

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026