Skip to content

A multicenter, randomized, controlled clinical study of alfentanil for dressing change analgesia in burn patients

A multicenter, randomized, controlled clinical study of alfentanil for dressing change analgesia in burn patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049119
Enrollment
Unknown
Registered
2021-07-21
Start date
2021-08-01
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burns

Interventions

Alfentanil group:The optimal dose of alfentanil was determined for continuous pumping
Control group:Continuous pumping of the same volume of normal saline

Sponsors

Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Burn patients undergoing wound dressing change; 2.Patients ranged in aged 18 to 65 years; 3.The burn site of the patient is not limited, the burn depth is I-II degree, the burn area is between 1-50%; 4.ASA classification I- III; 5.BMI 18.5 ~ 23.9 kg/m^2; 6.Patient or client signs informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients with a history of mental illness or disorder of consciousness who are unable to cooperate and who use antianxiety drugs or sedatives for a long time (>1 week); 2.Patients with a history of chronic pain (e.g. toothache, stomachache, headache, etc.); 3.Patients with severe organ dysfunction; 4.Patients with inhalation lung injury undergoing tracheotomy and mechanical ventilation; 5.Patients did not survive more than 24 hours after treatment.

Design outcomes

Primary

MeasureTime frame
Visual analogue scoring;Verbal Rating Scale;

Secondary

MeasureTime frame
Patient satisfaction;Total amount of alfentanil application, times and doses of intraoperative alfentanil addition;Whether to use oxygen, airway intervention;Whether other medications are used for intervention;

Countries

China

Contacts

Public ContactZhuang Lei

Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

leileihead@hotmail.com+86 13918846596

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026