Deep muscle relaxation
Conditions
Interventions
Control group:None
S1 group:Inhaled 0.7MAC sevoflurane
S2 group:Inhaled 1.3MAC sevoflurane
Sponsors
The First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Patients who planned to undergo single-port laparoscopic gynecological surgery under general anesthesia; 2.Fully informed and signed the informed consent; 3.Aged 18 to 60 years; 4.ASA rating I-III level; 5.Operation time <2 hours.
Exclusion criteria
Exclusion criteria: 1.Allergy to sevoflurane or propofol; 2.Patients with a history of severe cardiovascular, respiratory, liver, kidney, central nervous system or muscle diseases; 3.Obesity (BMI value> 30); 4.Definite or suspicious history or family history of malignant high fever; 5.Pregnant or lactating women; 6.Patients with sepsis; 7.Patients with intraoperative hypothermia (oropharyngeal temperature<35.5?).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The total dose of muscle relaxants during the maintenance period of general anesthesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Indicators of muscle relaxation recovery;Muscle relaxant antagonist dose;Recovery time of spontaneous breathing;Extubation time;Time out of the post-anesthesia care unit;Consciousness recovery time;Quality of awakening period;Pneumoperitoneum pressure;Surgeon's rating of surgical space conditions;Blood pressure;Heart rate;Depth of anesthesia;Postoperative complications;Postoperative pain score;C-reactive protein;Interleukin - 6;Postoperative cognitive function;Length of stay;Hospitalization expenses; | — |
Countries
China
Contacts
Public ContactGuo Yuanyuan
The First Affiliated Hospital of Chongqing Medical University
Outcome results
None listed