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Esketamine for postoperative analgesia in elderly patients undergoing hip surgery

Esketamine for postoperative analgesia in elderly patients undergoing hip surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100049082
Enrollment
Unknown
Registered
2021-07-20
Start date
2021-07-20
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative analgesia of hip surgery

Interventions

Experimental group 2:Esketamine+Sufentanil
Control group:Sufentanil

Sponsors

Shanghai Zhongye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing hip surgery; 2. Over 65 years old, no gender limitation; 3. ASA grade I-III; 4. Understand the study in detail and voluntarily signed the informed consent before the study.

Exclusion criteria

Exclusion criteria: 1. Patients with severe complications, mental illness, severe liver or kidney dysfunction, respiratory dysfunction, circulatory instability, etc. 2. Patients allergic to the active ingredient of esketamine or the used anesthetics. 3. Patients with elevated intraocular pressure (such as glaucoma) and increased intracranial pressure. 4. Patients with severe hypertension, coronary heart disease and diabetes mellitus. 5. Poor compliance or drug abuse. 6. Patients are unable to communicate effectively with the researchers or are considered inappropriate by the researcher.

Design outcomes

Primary

MeasureTime frame
pain score;PCA times;

Secondary

MeasureTime frame
postoperative delirium;nausea and vomiting;respiratory depression;

Countries

China

Contacts

Public ContactYang Shikey

Shanghai Zhongye Hospital

shikey001@163.com+86 15800638029

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026