postoperative pain
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18-80 years; 2. ASA I - III level; 3. Subjects who underwent orthopedic surgery for elective open reduction and internal fixation of ankle fractures; 4. Voluntarily participated and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Preoperative combined peripheral nerve injury or disease; 2. Long-term oral painkillers for chronic pain; 3. Serious compound trauma; 4. Pregnant women; 5. A history of steroid use within two weeks of the study; 6. There are contraindications for regional block; 7. Patients with contraindications to dexamethasone (mental health disorders, cataracts, glaucoma, bacteremia and systemic fungal infections, peptic ulcer disease, viral infections such as herpes or recent live vaccines); 8. The patient has a history of allergy to the study drug, a diabetic patient; 9. The wound is infected.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rebound pain;sleep quality during the night of surgery day and POD1;Blood inflammation related indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of sensory and motor nerve block;Patient satisfaction;Patient satisfaction score;Patient satisfaction score; | — |
Countries
China
Contacts
The Third Affiliated Hospital of Hebei Medical University