Mechanically ventilated patients
Conditions
Sponsors
Henan Provincial People`s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 60 years; 2. BMI is 18kg/m2-28kg/m2; 3. The expected mechanical (tracheal intubation) ventilation time in the ICU is more than 24 hours; 4. Estimated ICU hospitalization time >= 48 hours; 5. Patients or their family members voluntarily participated in this study and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnancy or breastfeeding; 2. Have a history of alcohol or drug abuse, mental illness or severe cognitive impairment; 3. Severe chronic liver disease (Child-Pugh grade B or C); 4. Bradycardia (II/III degree atrioventricular block), right bundle branch block; 5. Acute myocardial infarction or severe heart failure (NYHA class IV); 6. Patients allergic to remazolam tosylate; 7. Myasthenia gravis patients, coma (GCS score <= 8 points); 8. Participate in clinical trials of other drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of achieving sedation goals with a single medication and other indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| duration of ICU stay?duration of Mechanical ventilation and other indicators; | — |
Countries
China
Contacts
Public ContactQin Bingyu
Henan Provincial People's Hospital
Outcome results
None listed