Depressive disorder and Bioplar disorder
Conditions
Interventions
Control group:No
Sponsors
The Affiliated Brain Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
9 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Patient group: (1) Meet the diagnostic criteria of DSM-5 depressive disorder; (2) Never taking medication or taking continuous psychiatric medication for less than 14 days; (3) Aged 9-18 years old; (4) Voluntarily participate in this study and obtain the written informed consent of the legal guardian. 2. Normal control group: (1) 1. There is no previous or current mental disorder that meets the DSM-5 diagnostic criteria; (2) Aged 9-18 years old; (3) Voluntarily participate in this study and obtain the written informed consent of the legal guardian.
Exclusion criteria
Exclusion criteria: 1. Patient group: (1) Nervous system diseases, brain organic diseases and mental disorders caused by physical diseases; (2) Developmental disorders other than ADHD, including: IQ <=70 or mental retardation, autism spectrum disorder, obvious dyslexia, tic disorder, etc.; (3) Any psychoactive substance use, abuse or dependence before the illness; (4) Severe active physical disease. 2. Normal control group: (1) Have a family history of mental disorders; (2) Central nervous system diseases; (3) Severe active physical disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| bipolar disorder high risk assessment;self-harm, suicidal thoughts and behaviours;Alcohol or substance abuse; Physical health comorbidities;envirnmental factors;functional outcomes;neurocognative functions;circadian rythm marker;plasma/serum biomarkers;genetic analysis;Brain structure and function information;Event-related potential, eye movement;near-infrared imaging;intestinal flora; | — |
Secondary
| Measure | Time frame |
|---|---|
| clinical presentation; | — |
Countries
China
Contacts
Public ContactCao Liping
The Affiliated Brain Hospital of Guangzhou Medical University
Outcome results
None listed