The oligopeptides of bovine bone collagen promote wound healing via PI3K/Akt/mTOR signaling pathway and its possible mechanism

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100049054

Enrollment

Unknown

Registered

2021-07-20

Start date

2021-08-01

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastrointestinal disease

Interventions

Control Group:Regular diet

Bovine collagen oligopeptide intervention group:Bovine collagen oligopeptide

Eligibility

Sex/Gender

All

Age

18 Years to 59 Years

Inclusion criteria

Inclusion criteria: 1. Patients who need gastrointestinal surgery; 2. Between 18 and 65 years old; 3. During the trial period, the medication situation was basically stable; 4. Voluntarily participate in the trial, be able to follow the trial protocol, and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Those who are allergic to drugs and/or food; 2. Those with severe heart, liver, brain and kidney failure; 3. Those who have participated in other clinical trials within 4 weeks; 4. Patients with other diseases or factors that affect absorption, distribution, metabolism and excretion.

Design outcomes

Primary

Measure	Time frame
Nutrition indicators;The immune indexes;	—

Secondary

Measure	Time frame
Inflammatory biomarkers;	—

Countries

China

Contacts

Public ContactBao Lei

Peking University International Hospital

baolei@pkuih.edu.cn+86 10 69007637

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026