Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Solid organ transplant recipients; 2. One dose of inactivated COVID-19 vaccine has been administered, and the second dose has not yet been administered; 3. Aged 18 to 65, male or female; 4. No serious infectious diseases such as severe pneumonia or severe immune dysfunction such as acute rejection occurred in at least 3 months; 5. Informed consent of the patient and written consent.
Exclusion criteria
Exclusion criteria: 1. People who are allergic to the active substance in the COVID-19 vaccine, any inactive substance or substance used in the preparation process, or who have developed allergies to previous COVID-19 vaccination; 2, Allergic physique; 3. Patients with fever or acute disease; 4. Complicated with serious heart and lung diseases; 5. Pregnant and lactating women, as well as women of reproductive age who do not wish to use contraception; 6. As judged by the investigator, subjects are unlikely to comply with the study visit arrangement or have a history of poor compliance; 7. Subjects have medical or psychiatric conditions that, as judged by the Investigator, may affect compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| neutralizing antibody;T cell response;Renal graft function; | — |
Secondary
| Measure | Time frame |
|---|---|
| urine protein;peripheral blood leucocyte;peripheral blood lymphocyte; | — |
Countries
China
Contacts
The Second Affiliated Hospital of Guangzhou Medical University