MRI-navigated repetitive transcranial magnetic stimulation to modulate motor and attention function in children with tic disorder

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100049029

Enrollment

Unknown

Registered

2021-07-20

Start date

2021-07-18

Completion date

Unknown

Last updated

2022-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

children with tic disorder

Interventions

New Method Targeting Group:cTBS

Classic targeting group:cTBS

healthy control group:NO

Eligibility

Sex/Gender

All

Age

6 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for TS (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, DSM-V); 2. Yale Global Tic Severity Scale (YGTSS) total score >= 25; 3. Symptoms persist for more than 1 year, and the drug regimen has not been adjusted within one month; 4. Right-handed; 5. Age 6-18 years old; 6. Able to accept TMS therapy, I and my guardian agree to be treated and observed in accordance with this study. TMS treatment targets are limited to TS patients.

Exclusion criteria

Exclusion criteria: 1. RS-fMRI scanning head movement is greater than 3mm3 degrees; 2. Failure to complete TMS stimulation.

Design outcomes

Primary

Measure	Time frame
Yale Comprehensive Tic Severity Scale (YGTSS);inhibitory control;sustained attention;functional connectivity;LFO amplitude;Structral connectivity;total clinical efficacy scale;	—

Countries

China

Contacts

Public ContactZang Yufeng

Hangzhou Normal University

zangyf@hznu.edu.cn+86 18606517380

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026