Knee osteoarthritis
Conditions
Interventions
Load experimental group:Loaded hip and knee joint strengthening
Experimental group:Hip and knee joint strengthening
Control group:Conventional rehabilitation
Sponsors
The First Hospital of Jinan University
Eligibility
Sex/Gender
Female
Age
45 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Female patients between the ages of 45 to 80 years; 2. Meet the diagnostic criteria of knee osteoarthritis (KOA), that is, meet the main complaint of "recurrent knee pain in the past 1 month" and 2 of the following conditions: X-ray in standing or weight-bearing position The radiograph shows narrowing of the joint space, subchondral bone sclerosis and/or cystic degeneration, and osteophytes on the edge of the joint; the morning stiffness is generally less than 30 minutes; the bone friction sound (feel) is occasionally felt during active activities; 3. The Kellgren-Lawrence (KL) classification of the full-length X-ray of the lower extremities in the standing position before surgery is grade IV, which meets the indications for TKA surgery; 4. The preoperative assessment of the patient's hip abductor and knee extensor strength is grade 4-5; 5. The Advance medial pivot knee prosthesis (MP) of Shanghai MicroPort Corporation was used during the operation; 6. The chief surgeon of TKA operation is the same clinician with rich clinical experience and familiar with the TKA operation process and MP prosthesis design concept; 7. Perform unilateral TKA surgery. During the TKA procedure, the treatment of the infrapatellar fat pad was excision of 1/3-2/3; no resurfacing of the patella was performed; and peripatellar denervation was performed with electrocoagulation after patelloplasty.
Exclusion criteria
Exclusion criteria: 1. Patients with mental disorders or mental illnesses; 2. Complaints of hip or low back pain, who have undergone total hip replacement and knee collateral ligament reconstruction. History of proximal tibial or distal femoral osteotomy; 3. Body mass index BMI greater than 30kg/m2; 4. The lower limb muscle strength test before TKA is grade 3 or below, or the time spent in wheelchair is more than three months; 5. Diseases affecting the strength of the lower limbs in the past medical history, such as polio sequelae, Parkinson's disease, etc. Or suffer from diseases that affect subjective cognitive function, such as Alzheimer's disease, brain atrophy, etc.; 6. Diagnosed as Charcot joint disease or valgus deformity of lower limbs or severe varus deformity (greater than 30°) or extra-articular deformity of lower limbs with more than 10°; 7. Postoperative complications such as aseptic prosthesis loosening, periprosthetic fracture, periprosthetic infection and/or nonunion (or necrosis) of surgical incision occurred during the study; 8. The completion rate of the exercise content of the subjects in the experimental group is less than 80%.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster Universities Osteoarthritis Index, WOMAC;Forgotten Joint Score, FJS-12;Isometric muscle strength test;Gait test; | — |
Secondary
| Measure | Time frame |
|---|---|
| visual analogue scale;range of motion;Stair Climbing Test;Times up and Go; | — |
Countries
China
Contacts
Public ContactZha Zhengang
Jinan University
Outcome results
None listed