Acute and subacute superior mensenteric
Conditions
Interventions
experimental group:Transcatheter arterial thrombolysis
Sponsors
The First Medical Center, Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years; 2. The diagnosis of acute-subacute PV-SMV thrombus was confirmed by contrast-enhanced abdominal CT (acute phase [<=7 days], CT showed low density, and transition to subacute phase (7-14 days) showed high density); 3. Accompanied by abdominal pain, abdominal distension, nausea, anorexia, vomiting, fever and other symptoms, the course of the disease is within 14 days; 4. Abdominal symptoms (mainly abdominal pain) did not improve or worsened after 24 hours of intravenous anticoagulation therapy, extensive thrombosis and expected intestinal necrosis were more likely; 5. There are no other contraindications for angiography (such as iodine contrast agent allergy, uncontrolled infection, uncorrectable coagulation skills disorder, etc.); 6. The subjects voluntarily joined the study, signed the informed consent, and were able to cooperate with the follow-up and complete the research project.
Exclusion criteria
Exclusion criteria: 1. Chronic SMV-PV (the course of disease is more than 14 days, and CT scan shows abdominal wall thrombosis, collateral formation, etc.); 2. Intestinal necrosis, intestinal perforation, gastrointestinal bleeding; 3. Severe abnormal liver function (ALT/AST>=4ULN, DBIL>=3ULN) 4. Those with severe heart, lung, kidney, brain and other underlying diseases who cannot tolerate interventional therapy; 5. Combined with active bleeding of other organs; 6. Bilateral Allen test positive.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| disease control rate; | — |
Countries
China
Contacts
Public ContactWang Maoqiang
The First Medical Center, Chinese PLA General Hospital
Outcome results
None listed