Lung cancer
Conditions
Interventions
Group 1:Megestrol Acetate
Group 2:Megestrol Acetate Combined with Oral Nutrition Supplement
Sponsors
Shaanxi Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Histologically confirmed lung cancer patients (18 to 80 years old), nutritional risk score (NRS) >= 3, patient subjective global assessment (PG-SGA) score >= grade B, Eastern Cooperative Oncology Group (ECOG) score = 6 months; 2. Patients can receive anti-tumor chemotherapy, targeted therapy or palliative drug therapy or best supportive care at the same time. Opioids are used to treat cancer pain. The subjects voluntarily participated in this study and signed the informed consent form, and the compliance was good.
Exclusion criteria
Exclusion criteria: Women of child-bearing age and patients with mechanical obstruction to feeding, drug-induced changes in body weight (corticosteroids for prevention of chemotherapy-induced emesis were allowed), thromboembolism, diabetes mellitus, cardiovascular diseases, such as congestive heart failure (New York Heart Association, NYHA >= III), uncontrolled hypertension (systolic pressure > 140 mmHg and diastolic pressure > 90 mmHg), previous myocardial infarction, unstable angina, uncontrolled arrhythmia, previous cerebrovascular accidents, in?ammatory bowel diseases, or gastrointestinal ulcers were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body mass index;ECOG score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Appetite;Mid-upper arm circumference;Serum pre-albumin;Serum albumin; | — |
Countries
China
Contacts
Public ContactDuan Baojun
Shaanxi Provincial People's Hospital
Outcome results
None listed