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Multicenter efficacy study of multi-sequence therapy in the treatment of irreversible anterior disc displacement of temporomandibular joint

Multicenter efficacy study of multi-sequence therapy in the treatment of irreversible anterior disc displacement of temporomandibular joint

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048985
Enrollment
Unknown
Registered
2021-07-19
Start date
2021-07-22
Completion date
Unknown
Last updated
2022-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Temporo-mandibular Joint disease

Interventions

Group 1:conventional treatment + wearing a stable bite plate
Group 2:conventional treatment + intra-articular sodium hyaluronate injection + wearing a stable bite plate
Group 3:conventional treatment + injection in the retrodiscal area + wearing a stable occlusal plate

Sponsors

Third Affiliated Hospital of Air Force Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Aged 15-50 years; 2. Basic physical condition is good; 3. Clinically diagnosed as irreversible anterior disc displacement according to DC/TMD criteria: (1) Medical history or chief complaint of locking or jamming of the mandible, and currently has joint locking and restricted opening, which affects eating; (2) Passive opening <35mm (including incisor overbite distance); (3) On MRI images, the articular disc is located in front of the condyle in the closed position and the maximum open position; 4. The course of the disease is within 3 months; 5. Understand and accept the research content, and voluntarily sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Received other TMD-related treatments recently; 2. There is a history of serious systemic diseases and special drug allergies; 3. There are special oral diseases and cannot receive corresponding treatment; 4. Have a history of mental illness; 5. There is obvious craniofacial deformity or asymmetry.

Design outcomes

Primary

MeasureTime frame
Evaluation of Mandibular Functional Limitation Scale;

Countries

China

Contacts

Public ContactYu Shibin

Third Affiliated Hospital of Air Force Medical University

yushibin@fmmu.edu.cn+86 13609195296

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026