Ineffective esophageal motility (IEM)
Conditions
Interventions
Sponsors
Chengdu Third People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the diagnostic criteria of GERD and have ineffective esophageal motility; 2. Aged 18 to 70 years; 3. The patient has symptoms such as heartburn and reflux, which occur at least twice a week; 4. Not taking antacids, gastrointestinal motility drugs and other drugs that affect esophagus and gastrointestinal motility within the past 1 week; 5. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Obstructive lesions of the esophagus; 2. Combined with other esophageal motility disorders such as EGJ outflow tract obstruction (achalasia, mechanical obstruction) and severe esophageal motility disorders (distal esophageal spasm, esophageal asystole, esophageal hypercontraction); 3. There is any grade of esophageal intraepithelial neoplasia or esophageal cancer, esophageal polyps, esophageal varices or ulcers, history of esophageal or gastric surgery, and hiatal hernia >=3cm; 4. There are systemic diseases, including connective tissue diseases such as systemic sclerosis, Sj?gren's syndrome, and blood system diseases such as amyloidosis; 5. Patients with severe cardiovascular and cerebrovascular, liver, kidney and hematopoietic system diseases and mental illness; 6. Pregnant and lactating patients; 7. Those who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measurement of esophageal motility; | — |
Secondary
| Measure | Time frame |
|---|---|
| Reflux event;Clinical symptoms;Quality of life; | — |
Countries
China
Contacts
Public ContactWang Qiong
Chengdu Third People's Hospital
Outcome results
None listed