Gitelman syndrome
Conditions
Interventions
Case series:None
Sponsors
PLA General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The clinical manifestations are infection or skeletal deformity, short stature, muscle weakness, etc.; 2. Children with low or normal blood pressure; 3. Children with chronic hypokalemia (blood K+ concentration <3.50mmol/L) accompanied by renal potassium loss; 4. With or without hypomagnesemia (blood Mg2+ concentration <0.66mmol/L); 5. Hypocalciuria [urine 24hCa2+ concentration <0.1mmol/(kg??d) or single urine Ca2+ concentration/creatinine concentration <0.21; 6. Metabolic alkalosis; 7. RAAS system activation (increased plasma renin, angiotensin, aldosterone levels or increased activity).
Exclusion criteria
Exclusion criteria: 1. Long-term use of laxatives and diuretics; patients with primary or secondary glomerulonephritis, nephrotic syndrome and other diseases; 2. Combined with other chronic diseases, such as hypothyroidism, growth hormone deficiency and other diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease genes; | — |
Countries
China
Contacts
Public ContactXiao Donghua
Chinese People's Liberation Army General Hospital
Outcome results
None listed