Study on effective dose of S-ketamine, remifentanil and lidocaine in relieving pain of propofol injection in patients of different ages

Study on effective dose of s-ketamine, remifentanil and lidocaine in relieving pain of propofol injection in patients of different ages

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100048951

Enrollment

Unknown

Registered

2021-07-19

Start date

2021-09-01

Completion date

Unknown

Last updated

2022-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

S-ketamine Group:Intravenous in different doses

Remifentanil Group:Intravenous in different doses

Lidocaine Group:Intravenous in different doses

Eligibility

Sex/Gender

All

Age

3 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 3 to 80 years, gender is not limited; 2. Patients undergoing elective general anesthesia; 3. BMI 18.5-24.9kg/m^2; the child's weight is within two standard deviations (±2SD) of the weight in this age group; 4. ASA I or II; Mallampati I or II; 5. No contraindications for esketamine, remifentanil, lidocaine and propofol; 6. No history of drug abuse.

Exclusion criteria

Exclusion criteria: 1. Patients who refuse to participate or those who are not suitable to participate in this trial; 2. Difficult airway; 3. Severe cardiopulmonary and cerebrovascular diseases; 4. Allergy to esketamine, remifentanil, lidocaine, and propofol; 5. Have neuromuscular junction disease myasthenia gravis, schizophrenia, epilepsy, etc.; 6. Severe anemia, coagulation dysfunction, etc.

Design outcomes

Primary

Measure	Time frame
pain score;	—

Countries

China

Contacts

Public ContactTan Meiyun

Boai Hospital of Zhongshan, Affiliated to Southern Medical University

13726028414@163.com+86 13726028414

Outcome results