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Study on early diagnostic markers of necrotizing soft tissue infection

Study on early diagnostic markers of necrotizing soft tissue infection

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100048949
Enrollment
Unknown
Registered
2021-07-19
Start date
2015-11-01
Completion date
Unknown
Last updated
2022-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Necrotizing soft tissue infection

Interventions

Sponsors

Emergency Department of the First Affiliated Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1.Inclusion criteria for patients with necrotizing soft tissue infection (NSTI): highly suspected NSTI and surgical incision; 2.Inclusion criteria for non-NSTI patients: Patients with skin / soft tissue infection not up to the inclusion criteria for NSTI patients; 3.The criteria for healthy subjects were: age matched with NSTI patients and non NSTI patients without diabetes, hypertension, coronary heart disease, tumor, liver, kidney and autoimmune diseases.

Exclusion criteria

Exclusion criteria: 1.Aged < 18 years; 2.Patients with hospital stay less than 12 hours and incomplete clinical data; 3.Patients with skin diseases other than cellulitis and NSTI; 4.Patients with blood borne infectious diseases; 5.Patients enrolled in other clinical studies at the same time; 6.Patients unwilling to sign informed consent.

Design outcomes

Primary

MeasureTime frame
metabolite;gene(PLA2G6);SEN, SPE, ACC, AUC of ROC;

Countries

China

Contacts

Public ContactLu Zhongqiu

The First Affiliated Hospital of Wenzhou Medical University

352368881@163.com+86 13957759958

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026