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The application of two-level non-invasive ventilator in the prevention and treatment of hypoxemia undergoing esophagogastroduodenoscopy: a prospective randomized controlled study

The application of two-level non-invasive ventilator in the prevention and treatment of hypoxemia undergoing esophagogastroduodenoscopy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048932
Enrollment
Unknown
Registered
2021-07-19
Start date
2021-07-19
Completion date
Unknown
Last updated
2022-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypoxemia

Interventions

group A:oxygen via nasal cannula
group B:oxygen via a nasal noninvasive positive pressure ventilation mask with positive pressure

Sponsors

The Third Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients with BMI > 25 or more than 3 STOP-BANG scores who underwent esophagogastroduodenoscopy; 2. Aged 18-65 years; 3. Willing to accept the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. ASA grading >= 3, such as: combined with severe cardiovascular disease, uncontrolled diabetes, etc .; 2. Patients with abnormal abnormalities and neuropathy lead to abnormal sensation; 3. Patients with the history of allergic to drugs; 4. Patients with severe coagulation function; 5. Baseline blood oxygen saturation <95%.

Design outcomes

Primary

MeasureTime frame
Incidence of hypoxemia(75%15 seconds and < 60 seconds) during anesthesia;

Secondary

MeasureTime frame
Incidence of subclinical respiratory depression (90%5 seconds) during anesthesia;Incidence of severe hypoxia (SpO260 seconds) during anesthesia;Interventions are needed to deal with hypoxemia;Total dose of propofol;Operating time;Number of operation interruptions;Anxiety index score and satisfaction score of anesthesiologist (VAS score);Operator's anxiety index score and satisfaction score (VAS score);Incidence of postoperative nausea and vomiting;Incidence of postoperative dizziness and headache;

Countries

China

Contacts

Public ContactShen Ning

The Third Affiliated Hospital of Sun Yat-sen University

paulshenyh@163.com+86 13922289000

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026