melasma
Conditions
Interventions
control group:755 nm picosecond laser
experimental group:755 nm picosecond laser + tranexamic acid + transdermal delivery vehicle
Sponsors
Beijing Friendship Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed as chloasma according to ''Criteria for the diagnosis and treatment of chloasma and vitiligo (2010 edition)''; 2. Aged between 18 and 60 years; 3. Stable condition within the past 3 months; 4. Informed consent to this study and signed the informed consent; 5. Patients with good compliance and regular follow-up.
Exclusion criteria
Exclusion criteria: 1. Received treatment in the past six months (including systemic medication, external medication, chemical peeling, phototherapy, mesoderm therapy or other whitening treatments); 2. Outdoor workers who have been exposed to the sun in the past 3 months or have been exposed to sunlight for a long time; 3. During pregnancy, lactation, or pregnancy; 4. Severe heart, brain, liver, kidney, blood and other systemic diseases and immunodeficiency; 5. There is any facial skin disease that affects the diagnosis of chloasma or other pigmented diseases; 6. Light sensitivity, allergic to anesthetics; 7. Those who cannot avoid sunlight and sun protection after surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Melasma Area and Severity Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Doctor's Overall Evaluation;Patient Self-Assessment; | — |
Countries
China
Contacts
Public ContactYang Gaoyun
Beijing Friendship Hospital Affiliated to Capital Medical University
Outcome results
None listed