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Effect of different doses of Diprospan solution cocktail on postoperative analgesia after total knee arthroplasty

Analgesic effect of multimodal cocktail periarticular injection combined with Diprospan solution in total knee arthroplasty

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048876
Enrollment
Unknown
Registered
2021-07-19
Start date
2021-07-20
Completion date
Unknown
Last updated
2022-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total knee arthroplasty

Interventions

Control group:The cocktail without Diprospan solution was injected around the joint
Experimental group 1:A cocktail containing 1ml of Diprospan solution was injected around the joint
Experimental group 2:A cocktail containing 2ml of Diprospan solution was injected around the joint
Experimental group 3:A cocktail containing 3ml of Diprospan solution was injected around the joint

Sponsors

The First Affiliated Hospital of Xinjiang Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. Patients with TKA operation indications who underwent primary total knee arthroplasty; 2. Aged 18 to 80 years; 3. The patient volunteered and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Past or recent history of taking opioids; 2. Patients who are unwilling or unable to sign the informed consent, have mental illness, and are unable to complete the postoperative pain score; 3. There was a history of opioid, glucocorticoid or sulfonamide allergy before operation; 4. Patients who cannot tolerate anesthesia and surgery; 5. Patients who are participating in other clinical trials; 6. Researchers think that other reasons are not suitable for clinical trials.

Design outcomes

Primary

MeasureTime frame
visual analogue scale;American knee society score;range of motion;forget joint score;

Countries

China

Contacts

Public ContactWang Yang

The First Affiliated Hospital of Xinjiang Medical University

41481718@qq.com+86 13999864326

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026