Breast cancer
Conditions
Interventions
non-pCR cohort: Luminal breast cancer patients who did not achieve pathological complete response after neoadjuvant therapy:No interventions
pCR cohort: Luminal breast cancer patients who achieved pathological complete response after neoadjuvant therapy:No interventions
Sponsors
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged from 18 to 65 years, no gender limit; 2. Pathologically confirmed as primary breast cancer; 3. Pathologically confirmed by puncture as Luminal breast cancer, that is, ER and (or) PR positive>=1%+; 4. Accept and complete standardized neoadjuvant therapy; 5. The subject voluntarily participates in the research and agrees to sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Distant metastasis; 2. Transfer in the process of new assistance; 3. Patients with a second primary tumor; 4. Comprehensive evaluation, the researcher believes that it is not suitable to participate in this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence-Free Survival(RFS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall Survival(OS);Specificity/Sensitivity of ctDNA for Predicting Recurrence;Lead Time of ctDNA Detection;Postoperative ctDNA Status; | — |
Countries
China
Contacts
Public ContactGong Chang
Sun Yat-sen Memorial Hospital of Sun Yat-sen University
Outcome results
None listed