Female patients undergoing cervical conization
Conditions
Interventions
experimental group:Induction: Alfentanil 7µg/kg, Remazolam 0.2mg/kg
Maintenance: Remazolam 1mg/kg
control group:Induction: Alfentanil 7µg/kg, Propofol 1.5mg/kg
Maintenance: Propofol 6-8mg/kg
Sponsors
Xijing Hospital Fourth Military Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Female patients who have indications for surgery and plan to undergo cervical conization; 2. Aged from 18 to 65 years; 3. BMI 18.5-30 kg/m2; 4. ASA I-II; 5. Volunteer to participate and signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of serious heart, brain, lung, liver, kidney and metabolic diseases; 2. People with neuromuscular system disease or mental illness; 3. Suspected of abusing narcotic analgesics or tranquilizers; 4. Patients who are known to be allergic to emulsions, benzodiazepines and opioids; 5. Patients who do not cooperate and cannot communicate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of total adverse events in the respiratory and circulatory systems;Blood pressure;Heart rate;Oxygen saturation;Pco2 at end-expiratory;Breathing rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Loss of consciousness time, operation time, recovery time, time from waking up to leaving the operating room, Ramsay sedation score;Other intraoperative safety indicators;Satisfaction score; | — |
Countries
China
Contacts
Public ContactNie Huang
First Affiliated Hospital of Fourth Military Medical University
Outcome results
None listed