intermittent exotropia
Conditions
Interventions
Surgical treatment group:Nil
Healthy control group:Nil
Sponsors
Beijing Tongren Hospital affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Aged from 18 to 40 years; 2. Evidence of IXT on the basis of history and clinical examination; 3. Have surgical intention and meet the surgical indications including: loss of distant stereopsis using synoptophore and/or deflection time accounts for more than half of waking time, angle of deviation< -15?; 4. No ongoing or planned amblyopia treatment; 5. Best-corrected visual acuity better than or equal to 20/20 in both eyes, no anisometropia (< 1.50 D and < 1.00 D in the difference in spherical and cylindrical error, respectively); 6. Right handedness; 7. Be able to understand and cooperate with examinations, sign informed consent voluntarily.
Exclusion criteria
Exclusion criteria: 1. Structural ocular pathology; 2. Previous eye surgery history; 3. Accompanied by vertical strabismus; 4. History of diseases of central nervous system and the whole body; 5. History of psychiatric diseases including depressive disorder and delusional disorder; 6. Contraindication for MRI examination (treatable or accidental magnetizable metal in cardiac pacemaker or prosthesis or previous head or spinal trauma requiring neurosurgery, etc); 7. Claustrophobia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| resting-state BOLD-fMRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| ocular dominance;cover test;prism cover test;ocular movements;distance stereopsis;accommodative convergence/accommodation (AC/A) ratio;near stereopsis;visual perception examination(static stereopsis, perceptual eye position, and dynamic stereopsis);Newcastle Control Score evaluation; | — |
Countries
China
Contacts
Public ContactFu Jing
Beijing Tongren Hospital affiliated to Capital Medical University
Outcome results
None listed