thyroidectomy
Conditions
Interventions
Control group:Saline
S-ketamine group 1:0.25mg/kg intravenous injection
S-ketamine group 2:0.5mg/kg intravenous injection
S-ketamine group 3:1mg/kg intravenous injection
Sponsors
Jiangsu Provincial Hospital of Integrated Traditional Chinese and Western Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients who are older than 18 years old and younger than 60 years old under general anesthesia for thyroidectomy; 2. American Association of Anesthesiologists (ASA) grade I-III; 3. Body mass index BMI>18kg/m2, and BMI<30kg/m2; 4. Agree to participate in this study.
Exclusion criteria
Exclusion criteria: 1. Patients with hyperthyroidism; 2. Patients with mental illness or long-term use of psychotropic drugs; 3. Patients with allergies; 4. Patients with severe cardiovascular and cerebrovascular diseases; 5. Patients who recently participated in other studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressure;Cardiac output;Systemic vascular resistance;Stroke volume variation;Heart rate;Cardiac cycle efficacy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analog scale;Ramsay sedation score;Delirium score; | — |
Countries
China
Contacts
Public ContactMao Qinghong
Jiangsu Provincial Hospital of Integrated Traditional Chinese and Western Medicine
Outcome results
None listed