rheumatoid arthritis
Conditions
Interventions
control group:Nil
Sponsors
DongFang Hospital of Beijing University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Meet the above RA classification criteria; 2. Meet the diagnostic criteria of TCM syndromes; 3. Meet the criteria for judging the disease: DAS28 > 3.2 (active stage); 4. Aged from 18 to 70 years; 5. Not drink yogurt for nearly 1 week; 6. Not take antibiotics in the past three months; 7. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with inflammatory bowel disease, irritable bowel syndrome, persistent, transmissible gastroenteritis, colitis or gastritis; 2. Patients with cardiovascular, cerebrovascular, pulmonary, liver, kidney and hematopoietic system diseases and psychosis; 3. Patients with other rheumatic diseases such as systemic lupus erythematosus, Sjogren's syndrome, etc; 4. Positive human chorionic gonadotropin test; 5. Lactation period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of fecal cocci and bacilli;Fecal PH value;Toll-like receptor 4;myeloid differentiation factor 88;nuclear factor-kappa Bp65;T help 17 cells;Regulatory cells;diamine oxidase;D-LA;zonulin; | — |
Countries
China
Contacts
Public ContactWang Haiyu/Hou Xiujuan
Beijing University of traditional Chinese Medicine
Outcome results
None listed