Study on the characteristics of immune response in COVID-19 inactivated vaccine recipients

Analysis of the long-term characteristics of SARS-CoV-2 specific immunity and establishment of the accurate evaluation in COVID-19 inactivative vaccinated recipients

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100048837

Enrollment

Unknown

Registered

2021-07-18

Start date

2021-08-01

Completion date

Unknown

Last updated

2022-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Novel Coronavirus Pneumonia (COVID-19)

Interventions

Unvaccinated group:Nil

1st vaccination group:Nil

2nd vaccination group:Nil

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged >18 years, lacking the history of COVID-19 symptoms, RT-PCR positivity and IgM as well as IgG antibodies recognizing the spike and the nucleocapsid protein; 2. Unvaccinated or 1/2 dose(s) of unactivated COVID-19 vaccine complished.

Exclusion criteria

Exclusion criteria: 1. Having respiratory tract symptoms like fever, running nose and coughing within 1 month of the sampling time; 2. Autoimmune diseases; 3. Convalescent plasma therapy received; 4. Immunosuppressive drug therapy received or being received; 5. Pregnancy.

Design outcomes

Primary

Measure	Time frame
Interferon-gama;interleukin-2;tumor necrosis factor-alpha;SARS-CoV-2 NAb;SARS-CoV-2 RBD-IgG;	—

Countries

China

Contacts

Public ContactLiu Jia

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

jialiu77@hust.edu.cn+86 18696159826

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026