post covid 19 syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years 2. Discharged from hospital after a COVID19 pneumonia 3. In spontaneous breathing 4. Able to breathe keeping a mouthpiece 5. Mild to moderate obstructive syndrome at spirometry (12) and at least one symptom among: (1) Breathlessness or feeling as I can't take a deep breath or inability to yawn (2) Cough (3) Chest pain/Chest tightness (4) Dyspnoea (at rest or during normal ADL) (5) Oxygen desaturation >=4% during daily physical activities
Exclusion criteria
Exclusion criteria: - Already on treatment with NIV or CPAP before COVID 19 - Oxygen supplementation at rest - Inability or refusal to collaborate - Lack of informed consent - Severe obstructive syndrome ( forced expiratory volume 1 second - FEV1 - < 50% )
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcomes were changes in symptoms scores and CAT.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes were changes in respiratory function parameters, exercise capacity, respiratory muscles strength (MIP, MEP and SNIP ) and cough efficacy (PCEF); | — |
Countries
Italy