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Influence of driving pressure-guided individualized PEEP titration on heart-kidney function in patients undergoing laparoscopic surgery

Influence of driving pressure-guided individualized PEEP titration on heart-kidney function in patients undergoing laparoscopic surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048825
Enrollment
Unknown
Registered
2021-07-18
Start date
2021-08-02
Completion date
Unknown
Last updated
2022-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic gastrointestinal surgery

Interventions

control group:5cm PEEP
experimental group:driving pressure-guided individualized PEEP titration

Sponsors

Northern Jiangsu People's Hospital Anesthesiology Department
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1.Patients undergoing gastrointestinal surgery under general anesthesia; 2.Aged from 18 to 70 years; 3.ASA grade I-II; 4.LVEF>50%; 5.Expected operation time is greater than 120min.

Exclusion criteria

Exclusion criteria: 1.The patient refused to participate in the study and did not sign the informed consent; 2.Severe lung diseases, such as chronic obstructive pulmonary disease, pleural effusion, asthma, pneumothorax, previous chest surgery history such as lobectomy, etc; 3.Severe cardiovascular disease and liver and kidney dysfunction; 4.Have a history of neuromuscular dysfunction; 5.BMI>=30kg/m2; 6.Preoperative blood oxygen saturation<=90%.

Design outcomes

Primary

MeasureTime frame
Various indicators of the dual-chamber function measured by TEE;Blood gas analysis and publicly calculated indicators representing lung oxygen sum;The indicators measured by TEE represent renal hemodynamics;

Secondary

MeasureTime frame
General indicators of the patient;General data of the recovery room;

Countries

China

Contacts

Public ContactHu Jiarui

Northern Jiangsu People's Hospital Anesthesiology Department

921191244@qq.com+86 19962593381

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026