Uterine fibroids
Conditions
Interventions
control group:MHT treatment
experimental group:MHT + HIFU treatment
Sponsors
The Second Hospital of Hebei Medical University
Eligibility
Sex/Gender
Female
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Perimenopausal women aged 40-60; 2. Ultrasound or MRI diagnosis of combined uterine fibroids; 3. Single uterine fibroids, and the largest diameter is less than 5cm; 4. No symptoms related to uterine fibroids; 5. Have MHT indications and are willing to accept MHT treatment.
Exclusion criteria
Exclusion criteria: 1. MHT treatment contraindications: (1) Known or suspected pregnancy; (2) Unexplained vaginal bleeding; (3) Known or suspected breast cancer; (4) Known or suspected sex hormone-dependent malignant tumors; (5) Active venous or arterial thromboembolic disease in the past 6 months; (6) Severe liver and kidney dysfunction; (7) Hematoporphyria, otosclerosis; (8) Currently suffering from meningioma (progesterone is prohibited); 2. HIFU treatment contraindications: (1) Combined with serious organic diseases of vital organs: uncontrollable hypertension, history of cerebrovascular accident, history of myocardial infarction, severe arrhythmia, heart failure, renal failure and liver failure, etc, accompanied by collagen connective History of tissue disease and radiotherapy of lower abdomen; (2) Acoustic channel abnormality: the width of the lower abdomen scar is >=1cm, the acoustic channel is abnormal in the localization check; there is a foreign body in the acoustic channel, etc; (3) Acute inflammation of the pelvic cavity or reproductive tract; (4) Patients with other gynecological malignant diseases, cervical or endometrial precancerous lesions or cancerous changes, and ovarian tumors; (5) Those who have language communication difficulties and cannot cooperate with sedation and analgesia programs; (6) Those who cannot lie on their stomachs for 1 hour.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fibroid volume; | — |
Countries
China
Contacts
Public ContactHe Xiaojing
The Second Hospital of Hebei Medical University
Outcome results
None listed