Skip to content

A random study: The effects of internal sphincterotomy of the anus on defecation disorders in patients with outlet obstructive and mixed constipation

A random study: The effects of internal sphincterotomy of the anus on defecation disorders in patients with outlet obstructive and mixed constipation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048818
Enrollment
Unknown
Registered
2021-07-17
Start date
2014-06-06
Completion date
Unknown
Last updated
2022-03-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Outlet obstructive and mixed constipation

Interventions

traditional medical treatment group:traditional medical treatment
Experimental group:internal sphincterotomy

Sponsors

The People's Hospital of Dazu District (Chongqing)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
36 Years to 58 Years

Inclusion criteria

Inclusion criteria: 1. great effort required in at least 25% of defecation attempts; (1) dry or hard stools accounting for at least 25% of bowel movements; (2) the sense of incomplete evacuation after defecation at least 25% of the time; (3) anorectal obstruction and blockage occurring in at least 25% of defecation attempts; (4) manual assistance (e.g., assistance with fingers or pelvic floor support) required for defecation at least 25% of the time; (5) infrequent defecation (fewer than 3 times per week); 2. Patient seldom had loose stools when laxatives were not used; 3. Patient did not meet the diagnostic criteria for irritable bowel syndrome; 4. During repeated attempts to defecate, the patient met at least 2 of the following 3 criteria: (1) diminished defecation confirmed by balloon expulsion test or imaging examination; (2) a diagnosis of absonant contraction of the pelvic floor muscles (e.g., the sphincter ani or puborectalis), or a resting pressure and relaxation rate of the sphincter of less than 20%, as determined by manometry, imaging examination, or electromyography; (3) a diagnosis of poor rectal propulsion during defecation by manometry or imaging examination.

Exclusion criteria

Exclusion criteria: 1. patients with constipation caused by organic diseases or drugs; 2. patients with systemic organic diseases in the heart, liver, kidneys, etc., or mental disorders; 3. patients with endocrine diseases and metabolic diseases, such as diabetes, thyroid disorders, etc.; 4. patients who were long-term users of medications, including sedatives, antidepressants, anticholinergic drugs, antipsychotic drugs, and calcium channel blocker agents; 5. patients with muscular diseases.

Design outcomes

Primary

MeasureTime frame
Treatment effectiveness evaluation;

Countries

China

Contacts

Public ContactBincheng Guo

The People's Hospital of Dazu, Chongqing, China

1047429335@qq.com+86 13969969713

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 14, 2026