polycystic ovary syndrome
Conditions
Interventions
conventional treatment group:Cycloprogesterone acetate combined with metformin
Vitamin D treatment group:Vitamin D supplement
Conventional treatment combined with vitamin D treatment group:Cycloprogesterone acetate combined with metformin, Vitamin D supplement
Sponsors
The First Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
Female
Age
20 Years to 39 Years
Inclusion criteria
Inclusion criteria: 1. Select PCOS as the research object. PCOS is based on the criteria established by the revised Rotterdam meeting: (1) oligoovulatory or anovulatory; (2) unilateral or bilateral ovaries contain 12 or more follicles with a diameter of 2-9 mm, and (or) Ovarian volume>10cm3; (3) Clinical manifestations or laboratory evidence of hyperandrogenism. If (1)(2) or (1)(3) or both of these three items are met, PCOS can be diagnosed; 2. At the same time, the patient has insulin resistance, IR diagnostic criteria: insulin resistance index (HOMA-IR) = fasting blood glucose x fasting insulin/22.5, IR criteria are fasting plasma insulin >= 20 mIU/L or HOMA-IR > 4.5 or G : I (fasting blood glucose: fasting insulin) < 4.5.
Exclusion criteria
Exclusion criteria: 1. Be younger than 18 years old or older than 45 years old; 2. Hyperandrogenemia and ovulation abnormalities caused by other factors; 3. Not receiving vitamin D treatment and follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metabolism-related index; | — |
Countries
China
Contacts
Public ContactWang Li
The First Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed