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A single-center, retrospective clinical study of differences in voriconazole use and plasma concentration

A single-center, retrospective clinical study of differences in voriconazole use and plasma concentration

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100048728
Enrollment
Unknown
Registered
2021-07-13
Start date
2021-12-31
Completion date
Unknown
Last updated
2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

invasive fungal infections

Interventions

case series:No

Sponsors

Second Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who were hospitalized and used voriconazole in the Second Xiangya Hospital of Central South University from May 2014 to December 2020; 2. No gender limit, no age limit; 3. Confirmed, clinically diagnosed or suspected IFI and patients with high risk factors for fungal infection; 4. Monitor the plasma concentration of voriconazole at least once at steady state (after 3 days of administration).

Exclusion criteria

Exclusion criteria: 1. Patients who cannot obtain accurate voriconazole dosage and main clinical data; 2. Plasma exchange therapy was performed during the concentration determination; 3. Patients known to be allergic to voriconazole or any of its components; 4. It is judged by the investigator that it is not suitable to participate in this research.

Design outcomes

Primary

MeasureTime frame
trough concentration;

Countries

China

Contacts

Public ContactYan Miao

Second Xiangya Hospital, Central South University

zhaoyichang@csu.edu.cn+86 731 85292097

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026