The effect of S-ketamine with dexmeditomidine on the incidence of postoperative delirium in surgical pediatric patients

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100048713

Enrollment

Unknown

Registered

2021-07-13

Start date

2021-07-13

Completion date

Unknown

Last updated

2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative delirium

Interventions

intervention group:S-ketamine with dexmeditomidine

Control group:saline

Eligibility

Sex/Gender

All

Age

2 Years to 16 Years

Inclusion criteria

Inclusion criteria: 1. Pediatric patients who intend to undergo elective surgery under general anesthesia; 2. The expected operation time is more than 1 hour; 3. Age 2 to 16 years old.

Exclusion criteria

Exclusion criteria: 1. Refuse to participate in this research; 2. Patients with neurological disease who cannot cooperate with delirium assessment; 3. Severe cognitive impairment cannot complete the delirium assessment; 4. Congenital vision or hearing impairment affects the assessment of delirium; 5. ASA grade IV and above.

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative delirium within 5 days;	—

Secondary

Measure	Time frame
Incidence of emergence delirium;postoperative 30-day complications and mortality;postoperative hospital length of stay;expense during hospital stay;biological indicator: preoperative an postoperative inflammatory factor and neurological injury markers;	—

Countries

China

Contacts

Public ContactMu Dongliang

Peking University First Hospital

mudongliang@icloud.com+86 10 83575138

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026