renal transplantation, invasive fungal infections
Conditions
Interventions
Test group:No
Sponsors
Second Xiangya Hospital, Central South University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Kidney transplant recipients, regardless of gender and older than 18 years old, who received outpatient follow-up or in-patient treatment in the Department of Kidney Transplantation, Second Xiangya Hospital of Central South University; 2.To receive the TAC, Mortimexophenate and Glucocorticoid triple immunosuppressive regimen; 3.Receiving kidney transplantation for the first time; 4.For patients receiving voriconazole in combination, TAC, voriconazole steady state valley concentration data and other relevant clinical data as well as CYP3A4/CYP3A5 genotype should be obtained.
Exclusion criteria
Exclusion criteria: 1. Patients who cannot obtain accurate information on the dosage and main clinical data of tacrolimus and voriconazole; 2. Concomitant use of other immunosuppressants other than the study drug; 3. Plasma exchange therapy was performed during the concentration determination; 4. Patients who are known to be allergic to tacrolimus, mycophenolate mofetil, glucocorticoids, voriconazole or any of the above-mentioned drugs; 5. It is judged by the investigator that it is not suitable to participate in this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| trough concentration; | — |
Countries
China
Contacts
Public ContactYan Miao
Second Xiangya Hospital, Central South University
Outcome results
None listed