Myasthenia Gravis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The first onset meets the diagnostic criteria for generalized myasthenia gravis; 2. Complete admission data, detailed condition description, complete disease course record and no obvious missing items; 3. Application of glucocorticoid therapy; 4. Aged over 18 years old; 5. The diagnosis of GMG was re-verified by at least two attending physicians or higher-level physicians based on typical clinical phenotypes and laboratory test results.
Exclusion criteria
Exclusion criteria: 1. Patients with other neuromuscular diseases or peripheral neuropathy; 2. Combined with serious cardiovascular and cerebrovascular, liver, kidney and hematopoietic system diseases, chronic severe infection, mental illness; 3. Pregnant or lactating women; 4. Those who use other immunosuppressants; 5. The application of traditional Chinese medicine including traditional Chinese medicine or acupuncture has been started before enrollment; 6. Those who have been enrolled in other clinical intervention studies and have conflicts with the observation of this topic; 7. Those who meet any of the above items will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the relapse rate after hormone reduction,The incidence rate of hormone complications,and conversion rate of Myasthenia gravis crisis;Myasthenia gravis quantitative score (qMGS),;myasthenia gravis complex scale (MGC);myasthenia gravis muscle scale (MMS);myasthenia gravis absolute and relative score (ARS-MG); | — |
Secondary
| Measure | Time frame |
|---|---|
| MG daily life scale (MG-ADL); | — |
Countries
China
Contacts
Zhejiang Provincial Hospital of Traditional Chinese Medicine