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Safety and efficacy of segmental isolation of superior vena cava for radiofrequency ablation in patients with atrial fibrillation

Safety and efficacy of segmental isolation of superior vena cava for radiofrequency ablation in patients with atrial fibrillation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048692
Enrollment
Unknown
Registered
2021-07-12
Start date
2021-07-15
Completion date
Unknown
Last updated
2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial fibrillation

Interventions

Group 2:Isolation of superior vena cava
Group 1:Non superior vena cava isolation

Sponsors

Department of Cardiology, He'nan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18 to 80 years; 2.Radiofrequency catheter ablation was performed for the first time, except for left atrial thrombus by transesophageal ultrasound or left atrial pulmonary vein CTA; 3.There are ECG which can be definitely diagnosed as atrial fibrillation, that is: P wave disappeared, replaced by F wave, frequency 350-600 times / min, QRS wave rhythm is absolutely irregular, RR interval is uneven, QRS wave shape is normal; 4.There were palpitation, chest tightness and other symptoms, or the application of antiarrhythmic drugs (AAD) was ineffective; 5.Electrophysiological examination was performed after bilateral pulmonary vein isolation, and tachycardia was induced to indicate the origin of superior vena cava or the potential of superior vena cava was active; 6.Sign informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients with thrombosis in left atrium; 2.Left ventricular ejection fraction was less than 35%, thyroid function was abnormal; 3.Previous history of AF radiofrequency ablation and CABG; 4.Severe valvular heart disease or after prosthetic valve surgery; 5.Previous superior vena cava stenosis, sinus node dysfunction, after the pacemaker implantation; 6.The left atrium was more than 60 mm; 7.Patients with consumptive diseases such as malignant tumor and life expectancy less than 1 year; 8.Patients cannot cooperate with the follow-up for various reasons.

Design outcomes

Primary

MeasureTime frame
recurrence of atrial fibrillation;

Secondary

MeasureTime frame
Incidence of complications;duration of procedure;duration of X-ray exposure;

Countries

China

Contacts

Public ContactChu Yingjie

Department of Cardiology, He'nan Provincial People's Hospital

ningyuanyao@163.com+86 13253561638

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026