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Multi-center clinical extension study of the scientific and technological achievements of interferon-a target injection for the prevention and treatment of herpes zoster neuralgia

A randomized, double-blind, positive-controlled, equivalent, multicentre clinical trial of interferon-a in the treatment of herpetic neuralgia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100048686
Enrollment
Unknown
Registered
2021-07-12
Start date
2021-07-19
Completion date
Unknown
Last updated
2022-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Herpetic neuralgia

Interventions

Experimental group:Interferon-a and lidocaine were injected into the target
Control group:The targets were injected with methylprednisolone sodium succinate and lidocaine

Sponsors

First Hospital of Shanxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Herpetic neuralgia with a course less than 3 months; 2.The trigeminal ganglion and cerviothoracic lumbosacral ganglion were involved, NRS > 4; 3.Aged 50 to 80 years, gender is not limited; 4.Volunteer to participate in the study and sign the written informed consent.

Exclusion criteria

Exclusion criteria: 1.Herpes infection at the puncture site; 2.Herpez zoster oticus, central nervous system invasion and disseminated herpes zoster and other special clinical types; 3.Allergic to interferon alpha and methylprednisolone sodium succinate; 4.Coagulation dysfunction, severe heart, liver and renal insufficiency; 5.Patients with congenital immunodeficiency or immunodeficiency and serious diseases such as tuberculosis and tumor; 6.Patients with poor coordination with mental disorders (including patients cannot perform NRS and sleep quality scores); 7.The researcher did not consider it appropriate to participate in this study.

Design outcomes

Primary

MeasureTime frame
Numeric rating scale;Incidence of postherpetic neuralgia;

Secondary

MeasureTime frame
PSQI;Number of nerve block treatments;Total dose of basic drugs;

Countries

China

Contacts

Public ContactXue Zhaoxia

First Hospital of Shanxi Medical University

xzx1284@126.com+86 13485371284

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026