sepsis
Conditions
Interventions
sodium bicarbonate Ringer's solution treatment group:this group of patients received sodium bicarbonate Ringer's solution for early fluid resuscitation
sodium lactate Ringer's injection treatment group:this group received sodium lactate Ringer injection for early fluid resuscitation
0.9% sodium chloride injection treatment group:patients in this group received 0.9% sodium chloride injection for early fluid resuscitation
Sponsors
Rushan People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 80 years; 2.Patients with infection or suspected infection, clinicians judged that rapid fluid resuscitation was needed; 3.qSOFA score >= 2; 4.The informed consent form was signed by the patient himself or his immediate family member.
Exclusion criteria
Exclusion criteria: 1.Patients with cardiac arrest; 2.Patients have emergency operation; 3.Pregnant or lactating women; 4.Patients with autoimmune system diseases; 5.Patients who need CRRT treatment; 6.Patients are not or unwilling to accept central venous catheterization, or who are contraindicated for catheterization.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effects of different crystal resuscitation fluid on PH, electrolyte and blood lactic acid levels of patients;Blood gas analysis;Volumetric reactivity;Macrocyclic - microcyclic coupling;Daily systemic infection-related sexual organ failure score;Mechanical ventilation time;28-day mortality rate; | — |
Countries
China
Contacts
Public ContactQiu Xiaowen
Rushan People's Hospital
Outcome results
None listed